Chondromalacia is an osteocartilaginous non-inflammatory pathology that consists in the progressive degeneration of the articular cartilage and the subchondral bone, found softening and fissures on the articular surface. This degenerative condition can appear from an acute injury of the temporomandibular joint (TMJ) or by the chronic friction (microtrauma) between the mandibular condyle and the temporal component of the fossa/eminence.  Also, it may be due to metabolic properties inherent to articular cartilage that predispose to a given individual. We can classify chondromalacia in 4 stages depending on the pathological stage of the joint according to the appearance of different signs found during the arthroscopy. Degree I (superficial): softening of the cartilage; cartilage appears edematous, being the most obvious arthroscopic sign the trace (fovea) that the pressure of any instrument of palpation leaves. Cartilage softening is caused by the degradation of the proteoglycans by the collagenases that are released by the damaged chondrocytes.